Stocks on Wall Street traded lower in the premarket on Wednesday, signaling for negative session after yesterday’s rally. Meanwhile, the Pfizer-BioNTech coronavirus vaccine has received emergency use approval in the United Kingdom.

The Dow Jones plunged 0.32% at 4:27 am ET, while the S&P 500 lost 0.14% at the same time. The Nasdaq 100 was flat at 4:26 am ET.

After yesterday's 18-month record high, the euro decreased by 0.07% to sell for $1.20638 at 4:26 am ET.